Polk Audio quietly unveils headphones made 'just for Android'

Polk Audio quietly unveils headphones made 'just for Android'

If you're itching to show your love for Google's mobile OS, Polk Audio has you covered with a trio of headphones made "just for Android" that have been freshly listed on their website. Aside from sporting a black and green color scheme fit for Mountain View's OS, the gear appears to be a simple re-branding of the firm's sports-minded UltraFit line of in-ear and on-ear headphones, which already pack phone and audio controls. The hardware doesn't seem to be available just yet, but audiophiles yearning to flaunt their Android pride with the gear will eventually be set back between $70 and $100. Hit the neighboring source links for the breakdown on each model.

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Via: Android Central

Source: Polk Audio (1), (2), (3)

Source: http://www.engadget.com/2012/12/04/polk-audio-made-for-android-headphones/

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Childhood trauma leaves mark on DNA of some victims

Monday, December 3, 2012

Abused children are at high risk of anxiety and mood disorders, as traumatic experience induces lasting changes to their gene regulation. Scientists from the Max Planck Institute of Psychiatry in Munich have now documented for the first time that genetic variants of the FKBP5 gene can influence epigenetic alterations in this gene induced by early trauma. In individuals with a genetic predisposition, trauma causes long-term changes in DNA methylation leading to a lasting dysregulation of the stress hormone system. As a result, those affected find themselves less able to cope with stressful situations throughout their lives, frequently leading to depression, post-traumatic stress disorder or anxiety disorders in adulthood. Doctors and scientists hope these discoveries will yield new treatment strategies tailored to individual patients, as well as increased public awareness of the importance of protecting children from trauma and its consequences.

Many human illnesses arise from the interaction of individual genes and environmental influences. Traumatic events, especially in childhood, constitute high risk factors for the emergence of psychiatric illnesses in later life. However, whether early stress actually leads to a psychiatric disorder depends largely on his or her genetic predisposition.

Research Group Leader Elisabeth Binder of the Max Planck Institute of Psychiatry examined the DNA of almost 2000 Afro-Americans who had been repeatedly and severely traumatised as adults or in childhood. One-third of trauma victims had become ill and was now suffering from post-traumatic stress disorder. The risk of developing post-traumatic stress disorder rose with increasing severity of abuse only in the carriers of a specific genetic variant in the FKBP5 gene. FKPB5 determines how effectively the organism can react to stress, and by this regulates the entire stress hormone system. The scientists hoped to cast light on the mechanisms of this gene-environment interaction by comparing modifications of the DNA sequence of victims who had not become ill with that of those who had.

The Munich-based Max Planck scientists were then able to demonstrate that the genetic FKBP5 variant does make a physiological difference to those affected, also in nerve cells. Extreme stress and the associated high concentrations of stress hormones bring about what is called an epigenetic change. A methyl group is broken off the DNA at this point, causing a marked increase in FKBP5 activity. This lasting epigenetic change is generated primarily through childhood traumatisation. Consequently, no disease-related demethylation of the FKBP5 gene was detected in participants who were traumatised in adulthood only.

Torsten Klengel, a scientist at the Max Planck Institute of Psychiatry, explains the findings of the study as follows: "Depending on genetic predisposition, childhood trauma can leave permanent epigenetic marks on the DNA, further de-repressing FKBP5 transcription. The consequence is a permanent dysregulation of the victim's stress hormone system, which can ultimately lead to psychiatric illness. Decisive for victims of childhood abuse, however, is that the stress-induced epigenetic changes can only occur if their DNA has a specific sequence."

This recent study improves our understanding of psychiatric illnesses which arise from the interaction of environmental and genetic factors. The results will help tailor treatment particularly for patients who were exposed to trauma in early childhood, thereby greatly increasing their risk of illness.

###

Torsten Klengel, Divya Mehta, Christoph Anacker, Monika Rex?Haffner, Jens C. Pruessner, Carmine M. Pariante, Thaddeus W.W. Pace, Kristina B. Mercer, Helen S. Mayberg, Bekh Bradley, Charles B. Nemeroff, Florian Holsboer, Christine M. Heim, Kerry J. Ressler, Theo Rein & Elisabeth B. Binder

Allele?specific FKBP5 DNA demethylation: a molecular mediator of gene?childhood trauma interactions

Nature Neuroscience 2012

Max-Planck-Gesellschaft: http://www.mpg.de

Thanks to Max-Planck-Gesellschaft for this article.

This press release was posted to serve as a topic for discussion. Please comment below. We try our best to only post press releases that are associated with peer reviewed scientific literature. Critical discussions of the research are appreciated. If you need help finding a link to the original article, please contact us on twitter or via e-mail.

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Source: http://www.labspaces.net/125649/Childhood_trauma_leaves_mark_on_DNA_of_some_victims_

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100,000 protest at presidential palace

CAIRO (AP) ? More than 100,000 Egyptians protested outside the presidential palace in Cairo on Tuesday, fueling tensions over Islamist leader Mohammed Morsi's seizure of nearly unrestricted powers and the adoption by his allies of a controversial draft constitution.

The outpouring of anger across the Egyptian capital, the Mediterranean port of Alexandria and a string of other cities pointed to a prolonged standoff between the president and a newly united opposition.

Morsi's opponents, long fractured by bickering and competing egos, have been re-energized since he announced decrees last month that place him above oversight of any kind, including by the courts, and provide immunity to two key bodies dominated by his allies: The 100-member panel drafting the constitution and parliament's upper chamber.

The decrees have led to charges that Morsi's powers turned him into a "new pharaoh."

The large turnout in Tuesday's protests ? dubbed "The Last Warning" by organizers ? signaled sustained momentum for the opposition, which brought out at least 200,000 protesters to Cairo's Tahrir Square a week ago and a comparable number on Friday to demand that Morsi rescind the decrees.

The huge scale of the protests have dealt a blow to the legitimacy of the new constitution, which Morsi's opponents contend allows religious authorities too much influence over legislation, threatens to restrict freedom of expression and opens the door to Islamist control over day-to-day life.

What the revived opposition has yet to make clear is what it will do next: campaign for a "no" vote on the draft constitution in a nationwide referendum set for Dec. 15, or call on Egyptians to boycott the vote.

Already, the country's powerful judges have said they will not take on their customary role of overseeing the vote, thus robbing it of much of its legitimacy.

Morsi was in the presidential palace conducting business as usual as the protesters gathered outside. He left for home through a back door as the crowds continued to swell, according to a presidential official who spoke on condition of anonymity because he was not authorized to speak to the media.

The official said Morsi left on the advice of security officials to head off "possible dangers" and to calm the protesters. Morsi's spokesman, however, said the president left the palace at the end of his normal work day, through the door he routinely uses.

The protest was peaceful except for a brief outburst when police used tear gas to prevent demonstrators from removing a barricade topped with barbed wire and converging on the palace.

Soon after, with the president gone, the police abandoned their lines and the protesters surged ahead to reach the palace walls. But there were no attempts to storm the palace, guarded inside by the army's Republican Guard.

Protesters also commandeered two police vans, climbing atop the armored vehicles to jubilantly wave Egypt's red, white and black flag and chant against Morsi. The protesters later mingled freely with the black-clad riot police, as more and more people flocked to the area to join the demonstration.

The protesters covered most of the palace walls with anti-Morsi graffiti and waved giant banners carrying images of revolutionaries killed in earlier protests. "Down with the regime" and "No to Morsi," they wrote on the walls.

"He isn't the president of all Egyptians, only of the Muslim Brotherhood," said protester Mariam Metwally, a postgraduate student of international law. "We don't feel like he is our president."

A giant poster emblazoned with an image of Morsi wearing a Pharaonic crown was hoisted between two street light posts outside the presidential palace. "Down with the president. No to the constitution," it declared.

"The scene at Itihadiya palace is a stab at the president's legitimacy and his constitutional declaration," opposition leader Hamdeen Sabahi told a private TV network. "The scene sends a message to the president that he is running out of time."

The massive gathering was reminiscent of the one outside the palace on Feb. 11, 2011 ? the day authoritarian president Hosni Mubarak stepped down in the face of an 18-day uprising that ended his 29-year regime.

Shouts of "Erhal! Erhal!" ? Arabic for "Leave! Leave!" ? and "The people want to topple the regime!" rose up from the crowd, the same chants used against Mubarak. This time, though, they were directed at his successor, Egypt's first democratically elected president.

"The same way we brought down Mubarak in 18 days, we can bring down Morsi in less," Ziad Oleimi, a prominent rights activist, told the crowds using a loudspeaker.

In Alexandria, some 10,000 opponents of Morsi gathered in the center of the country's second-largest metropolis, chanting slogans against the leader and his Islamic fundamentalist group, the Muslim Brotherhood.

The protests fueled Egypt's worst political crisis since Mubarak's ouster, with the country clearly divided into two camps: Morsi, his Muslim Brotherhood and their ultraconservative Islamist allies, versus an opposition made up of youth groups, liberal parties and large sectors of the public.

Tens of thousands also gathered in Cairo's downtown Tahrir Square, miles away from the palace, to join several hundred who have been camping out there for nearly two weeks. There were other large protests around the city.

Smaller protests by Morsi opponents were staged in the Islamist stronghold of Assiut, as well as in Suez, Luxor, Aswan, Damanhour and the industrial city of Mahallah, north of Cairo.

"Freedom or we die," chanted a crowd of several hundred outside a mosque in Cairo's Abbasiyah district. "Mohammed Morsi, illegitimate! Brotherhood, illegitimate!" they yelled.

Earlier Tuesday, several hundred protesters also gathered outside Morsi's residence in an upscale suburb. "Down with the sons of dogs. We are the power and we are the people," they chanted.

Morsi, who narrowly won the presidency in a June election, appeared to be in no mood for compromise.

A statement by his office said he met Tuesday with his deputy, his prime minister and several top Cabinet members to discuss preparations for the referendum. The statement suggested business as usual at the palace, despite the mass rally outside its doors.

Asked why Morsi did not address the crowds, Muslim Brotherhood spokesman Mahmoud Ghozlan said the protesters were "rude" and included "thugs and drug addicts."

The Islamists responded to the mass opposition protests last week by sending hundreds of thousands of supporters into Cairo's twin city of Giza on Saturday and across much of the country. Thousands also besieged Egypt's highest court, the Supreme Constitutional Court.

The court had been widely expected to declare the constitutional assembly that passed the draft charter illegitimate and to disband parliament's upper house, the Shura Council. Instead, the judges went on strike after they found their building under siege by protesters.

Morsi's Nov. 22 decrees were followed last week by the constitutional panel rushing through the draft constitution in a marathon, all-night session without the participation of liberal and Christian members. Only four women, all Islamists, attended the session.

The charter has been criticized for not protecting the rights of women and minority groups, and many journalists see it as restricting freedom of expression. Critics also say it empowers Islamic religious clerics by giving them a say over legislation, while some articles were seen as tailored to get rid of the Islamists' enemies.

___

Associated Press writer Maggie Michael contributed to this report.

Source: http://news.yahoo.com/100-000-protest-egypts-presidential-palace-232530692.html

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How Much Physical Space Does the Internet Take Up?

The internet is one of the most ethereal concepts in tech: it's nowhere and everywhere, all at once. But if you could measure the thing, how much physical space would it take up? More »

Source: http://feeds.gawker.com/~r/gizmodo/full/~3/dRO5JPY7b9c/how-much-physical-space-does-the-internet-take-up

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Removing sea defenses may reduce impact of coastal flooding

ScienceDaily (Dec. 3, 2012) ? A study involving a scientist from the University of Southampton, which shows that ensuring continued flood protection for low lying coastal areas may mean sacrificing cliff top communities to the sea, has won the 2012 Lloyds Science of Risk prize for Climate Change research.

Robert Nicholls, Professor of Coastal Engineering at the University of Southampton and co-author of this study, says the research -- which will be further developed in a new book he is leading, to be launched in Spring 2013 -- says that the benefits of protecting our coastline from erosion must be balanced against the impacts of coastal flooding.

"The trade-off between protecting cliffs and their role in naturally nourishing our protective beaches will lead to difficult decisions, especially as sea levels are rising and finance is in short supply. This requires strategic planning for the future."

Professor Nicholls was part of a research team from the Tyndall Centre for Climate Change Research which, by focussing on a 72km stretch of shoreline along the East Anglian coast, detailed the interconnection between the two risks of erosion and flooding and show that in some cases, allowing natural erosion could reduce the impact of flooding associated with rising sea levels.

Coastal defences put in place over the last century or so have re-shaped the UK coastline, artificially protecting some areas, but at the expense of beaches in adjacent areas.

This human-made situation increases the risk of flooding in low lying coastal settlements where beaches act as a natural flood defence. Beach levels can be artificially recharged, but maintaining this indefinitely along large stretches of coastline is costly and likely to be unsustainable.

Richard Dawson, Professor of Earth Systems Engineering at Newcastle University and lead author of this study, adds: "Coastal areas typify the environmental challenge our society faces -- their beauty and economic opportunities attracts settlement and they include some of our most important ecosystems and most productive farmland. Yet this exposes us to hazards such as erosion and flooding which will be exacerbated by sea-level rise.

"Clearly we can't, and wouldn't want to, remove all our sea defences, but there are difficult trade-offs to be made in prioritising coastal management measures.

"Our research provides a common platform to get all parties round the table -- local residents, policy-makers, insurers, scientists and farmers to name but a few -- to understand each other's perspectives, discuss potential compensatory arrangements, and collectively decide the best way forward."

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Source: http://feeds.sciencedaily.com/~r/sciencedaily/top_news/top_environment/~3/zHAV4N603Cg/121203082054.htm

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Syria denies plans to use chemical weapons

BEIRUT (Reuters) - Syria said on Monday it would not use chemical weapons against its own people after the United States warned it would take action against any such escalation.

The statements came amid media reports, citing European and U.S. officials, that Syria's chemical weapons had been moved and could be prepared for use in response to dramatic gains by rebels fighting to topple President Bashar al-Assad.

"Syria has stressed repeatedly that it will not use these types of weapons, if they were available, under any circumstances against its people," the foreign ministry said.

U.S. Secretary of State Hillary Clinton had earlier warned that Washington would take action if Syria used the weapons.

"I am not going to telegraph any specifics what we do in the event of credible evidence that the Assad regime has resorted to using chemical weapons against their own people, but suffice to say, we are certainly planning to take action if that eventuality were to occur," she said during a visit to Prague on Monday.

The opposition believe that Assad, who has upped his response to rebel gains in the 20-month-old revolt, could turn to heavier weapons and some have suggested he might use chemical weapons.

The rebels have begun to advance quickly in recent weeks after months of slow sieges to cut off army routes and supplies.

In the past few weeks, they seized several military bases around the country, and an oil field and hydro-electric dam in the northeast. Rebels are using anti-aircraft weapons to attack the military helicopters and fighter jets that have bombarded their positions with impunity until now.

DAMASCUS BOMBARDMENT

The main focus for the army in the past five days has been Damascus, where security forces are pushing back hard against the rebels and trying to seal the capital off from rebel-dominated suburbs.

The opposition-linked Syrian Observatory for Human Rights said the Syrian army was trying to take over Daraya, on the southern outskirts of Damascus, and was attacking rebels with rockets as it advanced into some parts of the town.

A Syrian security source said that the army had blocked three entrances into Daraya and was optimistic it could take the town. Rebels said they would be able to hold their ground.

"There have been several attempts to storm Daraya and each time the army has suffered major losses. This is not new," said activist Samir al-Shami, of the Syrian Youth Union in Damascus.

Other activists reported heavy bombardment of the towns of Deir al-Asafir and Beit Saham, which are close to the highway leading to Damascus International Airport, the scene of three days of heavy clashes that effectively closed the airport.

EgyptAir said it had resumed flights after a three day suspension, saying the situation around the airport was now stable. All other airlines contacted said their flights were still suspended, citing concerns by local staff that the road was still unsafe.

Rebels had been planning an advance on the capital, Assad's power base.

The army struck back around the airport last Thursday and since then the suburbs of Damascus have been rocked by fierce clashes and heavy shelling. Activists described continuous shelling that killed more than 56 people around Damascus. More than 200 people died across Syria on Sunday, according to the Observatory.

Neither side has the upper hand in the fighting around Damascus. A previous attempt by rebels last July to hold ground in the city was crushed, but the fighters fell back into the suburbs and nearby countryside.

The Observatory reported air and artillery bombardment in towns across Syria on Monday. An air strike on the northern border town of Ras al-Ain, which it said killed at least 12 people and wounded more than 30, prompted Turkey to scramble fighter jets along the border.

More than 40,000 people have died in the conflict, with hundreds more killed each week.

(Reporting by Erika Solomon; Editing by Giles Elgood)

Source: http://news.yahoo.com/forces-pound-damascus-suburbs-flights-resume-032322698.html

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Uganda cbank cuts key lending rate 50 bps to 12 pct

NEW YORK (Reuters) - Many executives say they're anxious about the U.S. fiscal cliff negotiations, but Dow Chemical Co's chief executive says he's more bothered by the messy Chinese leadership transition, which he believes is wreaking greater harm on global markets. "Markets have, in a holistic sense, really been suffering more from China's slowdown than any slowdown here in the United States," Andrew Liveris said during the company's investor day in New York on Monday. ...

Source: http://news.yahoo.com/uganda-cbank-cuts-key-lending-rate-50-bps-093820337--business.html

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Free Website Advertising ? Should You Replace PPC Advertising ...

? posted on Tuesday, December 4th, 2012 at 11:52 am by Oview

Many online marketers, both new and experienced, have used ppc advertising to advertise their website businesses.

PPC advertising; also known as pay per click advertising or ppc search marketing, has the potential to bring INSTANT traffic to your website.

Additionally, if you only wanted to advertise your brand online, then ppc advertising can allow you to publicize your brand or promote your business name on the Internet, often at little or no cost.

Many a time, however, internet marketing practitioners will encounter problems with their search marketing or ppc advertising campaigns.

An online marketer like you and I could potentially spend large amounts of money on ppc advertising, but yet not make any sales or generate targeted online leads. Some of us may remember watching the number of clicks and our ppc advertising costs rising continually but without having made any sales or acquired many email leads.

What could be worse is that you could end up getting jaded or disillusioned with ppc advertising methods and stop using them completely.

Certainly, setting up an effective ppc advertising campaign may well require a fair amount of time and effort, sometimes over multiple attempts of trial and error.

If you have tried ppc advertising, then you can probably remember all the keyword research, the webpages, tracking codes, keyword tracking systems, website analytics that you had to prepare and monitor?

As an online business owner doing your own website marketing, you would probably want the biggest website advertising ?bang? for your buck.

Now, enter the free website advertising methods and techniques, which are also options that you can consider as alternatives to ppc advertising.

Naturally, if you wanted to replace ppc advertising with free website advertising, you will need to learn how to apply online advertising and Internet marketing techniques like:

1) article marketing

2) marketing with online videos

3) using your own website blogs as a form of free website advertising

4) applying web 2.0 website advertising techniques to drive traffic to your website

Also, let?s not forget that you have the choice of doing forum posts, blog comments, and joint venture marketing, all of which can be very effective as methods of free website advertising.

Given the many choices for advertising your website for free, should you then choose to replace your existing ppc advertising with free website advertising?

Perhaps, one possible approach is this ? If you are not getting the ppc advertising results you want, then you can continue to learn the methods of ppc advertising, refine your techniques, and improve your pay per click advertising skills.

Meanwhile, it would certainly be a good idea for you to start learning and applying one or two other techniques in free website advertising.

The additional effort that you put into free website

pages: 1 2

Source: http://www.oview.net/advertising/free-website-advertising-should-you-replace-ppc-advertising-with-free-ways-to-advertise-your-site.html

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Laide Bakare joins the music industry with record label | Nigerian ...

By Olamide Jasanya

Nollywood actress, Laide Bakare has kicked off her journey into the music scene with the launch?of her record label, Simline Records.

The actress says her decision to set up a label is because of her interest in the growth of the music industry,?and that of the entertainment industry generally, ?Simline Records is borne out of my love for music and the art. My interest is solely to help identify, grow and support talented youths? she said.

Bakare made her acting debut in 1999 and recently won BON awards for best Costume for her movie Jejere,?which featured musician 9ice as a lead actor.

She says the movie and her label will be launched next year and will be tagged ?The Laide Bakare Experience?.

Source: http://thenetng.com/2012/12/laide-bakare-joins-the-music-industry-with-record-label/

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